There are 3 main tasks in this project. First, we assisted in reviewing the risk assessment information of chemical substances and provided registrants with consulting services. A total of 7 cases of new chemical substances and 147 cases of existing chemical substances were reviewed completely this year. During the review, we summarized the frequently asked questions and provided suggestions. Furthermore, we clarified the essential information needed in risk assessment for different levels of standard registration and provided principles of the information submission. We also held 3 helpdesk meetings to assist registrants in preparing risk assessment dossiers. Second, we analyzed the international trends and proposed strategies for accelerating registration applications. The method for screening and the tiered approach of risk assessment were established based on the research results of integrated evaluation methods at the state level. In the meantime, toluene was used as an example to practice the risk assessment process. We held 3 expert consultation meetings in order to improve data collection and application in the future. To promote hazard information application, we established the information disclosure documents for 30 substances. The hazard information from registrant’s dossiers and international databases were also summarized, and the results were used to complete the abstracts of hazard information for 3 substances. For filling the data gaps, we provided a flow chart for ecotoxicology data from transformation products to explain the hazard of original substances. Third, we built a model for selecting the priority substances which needed further detailed information. We also completed the information dossiers for 10 substances which were selected from this model. The details of data gaps and the suggestions for data filling were also provided. This year, this project provided the necessary information for hazard and exposure evaluation and those results could help to build the risk assessment system of chemicals in Taiwan.